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Building human fetal brains and neurons from stem cells
15:00 to 16:00 - 23rd January 2019
Faculty Club, Blegdamsvej 3 Copenhagen Get direction

Agnete Kirkeby

Danish Stem Cell Center, University of Copenhagen Pluripotent stem cells can be used to produce human subtype-specific neuronal cells for disease modelling and regenerative cell therapy. We have developed a highly efficient method to produce midbrain dopaminergic neurons from human embryonic stem cells, and based on promising results in rodent disease models, we are currently planning a pioneering clinical stem cell therapy trial in Parkinson’s Disease. To better study human neural subtype differentiation and human brain development, we have further tissue engineered a model of human neural tube development based on human embryonic stem cells and microfluidic gradients.