Annual meeting – Crossroads between metabolism and the brain

DSfN Annual meeting, May 14-15, 2018

Hotel Hesselet, Nyborg Strand

May 14 - May 15, 2018


Crossroads between metabolism and the brain

The central nervous system (CNS) has an important role in the regulation of food intake, insulin sensitivity and glucose metabolism. On the other hand, factors regulating glucose and lipid metabolism in the periphery critically affect brain function as well as the development of neurological and psychiatric disorders. Furthermore, the field of delivering therapeutics from the periphery to the CNS is rapidly developing and is of immense clinical interest.

The theme for the Annual Meeting in the Danish Society for Neuroscience 2018 is crossroads between metabolism and the brain. This year, we will bring together basic scientists, clinicians, epidemiologists and industry, and address topics including access to the brain, the brain and appetite regulation, gut to brain signaling, the brain and glucose metabolism, and how metabolism and neurological disorders intersect.

Monday May 14th

09.00 – Arrival, coffee and registration

10.00 - Welcome

Session 1: Mechanisms in appetite regulation

Chair: Simon Glerup, Aarhus University

10.10 – Niels Vrang, Gubra, Hørsholm

            The brain in energy homeostasis

10:40  - Henning Fenselau, Max-Planck Institute for Metabolic Research, Köln (Lundbeck Lecture)

            Synaptic plasticity in energy homeostasis

11.10 – Tune Pers, University of Copenhagen

            Single cell sorting of hypothalamic neurons

11.40 – Kristoffer Lihme Egerod, University of Copenhagen

            Gut to brain communication

12.10 - Lunch

Session 2: Case stories in appetite regulation

Chair: Niels Vrang, Gubra

13.10 – Lotte Bjerre Knudsen, Novo Nordisk, Måløv

            GLP-1 and appetite regulation

13.40 – Mads Kjølby, Aarhus University

            SorCS1 and appetite regulation

14.10 – Coffee and cake

Session 3: Natural and pharmacological access to the brain

Chair: Lotte Bjerre Knudsen, Novo Nordisk, Måløv

14.30 – Morten Nielsen, Aarhus University

            Receptor-mediated drug delivery to the brain

15.00 - Hans Christian Cederberg , University of Copenhagen

            Tanycytes as uptake mechanism to the brain

15.30 - Birger Brodin, University of Copenhagen

            In vitro modeling of the brain endothelium for drug delivery studies

16.00 - Kristian Strømgaard, University of Copenhagen

            Targeting receptor complexes in the brain

16.30 – Short coffee break

16.40 – DataBlitz 5x10 min (selected abstracts)

Organizer: Simon Glerup

17.30 - Break

18.30 – Drinks and Dinner

21.00 – Drinks and posters. The Gubra Brain Award

Tuesday May 15th

07.30 - Breakfast

Session 4: Exercise and the brain

Chair: Mads Kjølby, Aarhus University

08.30 – Maiken Nedergaard, KU

            Exercise and glymphatics

09.00 – Carl-Johan Boraxbekk, Umeå University and Danish Research Center for Magnetic Resonance, Copenhagen

            The effect of exercise on brain function measured by PET and MRI

Session 5: Crosstalk between metabolism and psychiatric disorders

Chair: Mads Kjølby

09.30 – Bente Finsen, SDU

            Inflammatory cytokines, metabolism and neurodegenerative disorders

10.00 – Søren D. Østergaard, AU

            Statins, SSRIs and their interplay in depression

10.30 - Coffee 

10.45 – John Dirk Nieland, Aalborg

            Can we treat CNS diseases by blocking lipid metabolism?

11.15 – Simon Glerup, AU

            PCSK9 and brain development

11.45 – Anders Fink Jensen, Psykiatrisk Center, Rigshospitalet, København.

            GLP-1 in psychiatric diseases.

12.15 – Concluding remarks

12.30 – Lunch and departure